Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 3/20 | 0.36 |
| ▸ | GSTM2 | P28161 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786432 | 0.91 | TSHR (0.42) | LMNATSHRALDH1A1GSTP1GSTM2 | |
| SCHEMBL4788634 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2HTTLMNARECQLTSHR | |
| SCHEMBL4787944 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2HTTLMNARECQLTSHR | |
| SCHEMBL4787431 | 0.79 | IDO1 (0.47) | SMN1; SMN2HTTLMNATSHRALDH1A1 | |
| SCHEMBL4746166 | 0.79 | TSHR (0.43) | SMN1; SMN2HTTLMNARECQLTSHR | |
| SCHEMBL4743021 | 0.79 | ALDH1A1 (0.42) | SMN1; SMN2HTTLMNARECQLTSHR | |
| SCHEMBL4787718 | 0.78 | TSHR (0.41) | SMN1; SMN2HTTLMNARECQLTSHR | |
| SCHEMBL4743057 | 0.77 | ALDH1A1 (0.47) | SMN1; SMN2HTTLMNARECQLTSHR | |
| SCHEMBL4786482 | 0.76 | TSHR (0.42) | LMNARECQLTSHRALDH1A1POLB | |
| SCHEMBL4785121 | 0.76 | TSHR (0.54) | SMN1; SMN2HTTLMNARECQLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | claimed |