Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787509 | 0.90 | PGR (0.44) | PGRKMT2AALDH1A1NPC1CLK1 | |
| SCHEMBL4786364 | 0.81 | PGR (0.47) | PGRKMT2AL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL4787901 | 0.81 | PGR (0.44) | PGRALDH1A1ESR1MAPT | |
| SCHEMBL4479814 | 0.80 | MAOA (0.35) | PGRKMT2APKML3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4247622 | 0.79 | MAOA (0.35) | PGRKMT2APKML3MBTL1ALDH1A1 | |
| SCHEMBL4247127 | 0.79 | KDM4E (0.47) | PGRKMT2APKML3MBTL1ALDH1A1 | |
| SCHEMBL4785581 | 0.79 | PGR (0.43) | PGRKMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL4071256 | 0.78 | MAPT (0.36) | KMT2APKML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL4072001 | 0.77 | BACE1 (0.40) | KMT2APKML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL4788972 | 0.77 | PGR (0.46) | PGRESR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | disclosed |