Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483308 | 0.79 | L3MBTL1 (0.34) | PGRMAPTMKNK1MKNK2KMO | |
| SCHEMBL4786364 | 0.79 | PGR (0.47) | PGRESR1MAPT | |
| SCHEMBL4245491 | 0.77 | PGR (0.35) | PGRMAPTTACR3CNR2 | |
| SCHEMBL4470420 | 0.77 | HRH4 (0.36) | PGR | |
| SCHEMBL4467633 | 0.77 | PSD (0.34) | PGRPSD | |
| SCHEMBL4788071 | 0.77 | PGR (0.43) | PGRESR1MAPT | |
| SCHEMBL4785581 | 0.77 | PGR (0.43) | PGRMAPT | |
| SCHEMBL4787901 | 0.76 | PGR (0.44) | PGRESR1MAPT | |
| SCHEMBL4787509 | 0.76 | PGR (0.44) | PGRESR1MAPT | |
| SCHEMBL4248613 | 0.73 | KDM4E (0.43) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | disclosed |