Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786364 | 0.83 | PGR (0.47) | PGRESR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4787509 | 0.82 | PGR (0.44) | PGRESR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4788071 | 0.81 | PGR (0.43) | PGRESR1ALDH1A1MAPT | |
| SCHEMBL4069470 | 0.79 | MAOA (0.37) | PGRSMN1; SMN2MAOAMAOB | |
| SCHEMBL4785581 | 0.78 | PGR (0.43) | PGRALDH1A1MAPT | |
| SCHEMBL4788972 | 0.76 | PGR (0.46) | PGRESR1MAPT | |
| SCHEMBL4063663 | 0.76 | MAOA (0.31) | PGRMAOAMAOB | |
| SCHEMBL4245321 | 0.75 | GAA (0.33) | PGRMAPTSMN1; SMN2 | |
| SCHEMBL4749923 | 0.71 | KDM4E (0.44) | PGRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4746294 | 0.70 | ALDH1A1 (0.43) | PGRALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | disclosed |