Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967658 | 0.79 | ALOX5 (0.37) | ALOX5GAACA2MEN1MAPT | |
| SCHEMBL2690986 | 0.77 | — | — | |
| SCHEMBL11086694 | 0.76 | CA2 (0.42) | ALOX5GAANPSR1CA2MAPK1 | |
| SCHEMBL11079970 | 0.76 | KMT2A (0.50) | GAANPSR1CA2MAPK1KMT2A | |
| SCHEMBL23330448 | 0.74 | SLC6A4 (0.39) | GAANPSR1CA2MAPK1KMT2A | |
| SCHEMBL11182311 | 0.74 | ALOX5 (0.39) | ALOX5CA2MAPK1KMT2AMEN1 | |
| SCHEMBL23330960 | 0.74 | ALOX5 (0.39) | ALOX5CA2MAPK1KMT2AMEN1 | |
| SCHEMBL10964741 | 0.73 | FABP4 (0.48) | NPSR1KMT2AMAPK8FABP4BCAT2 | |
| SCHEMBL10584739 | 0.72 | ALOX5 (0.34) | ALOX5CA2MAPK1KMT2AMEN1 | |
| SCHEMBL7160610 | 0.71 | ALOX5 (0.39) | ALOX5CA2MAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206417-B | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-115124520-A | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2022-09-30 | — | — | CN | disclosed |
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | disclosed |