Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788947 | 0.79 | ALOX5 (0.38) | ALOX5CA2MEN1MAPK8LTB4R | |
| SCHEMBL6651039 | 0.73 | HSP90AB1 (0.40) | MEN1KDM4ECYP1A2GAAMAPT | |
| SCHEMBL11182311 | 0.73 | ALOX5 (0.39) | ALOX5CA2MEN1MAPK8ICMT | |
| SCHEMBL30908996 | 0.72 | KEAP1 (0.59) | ALOX5KEAP1MEN1MAPK8KDM4E | |
| SCHEMBL3814101 | 0.72 | CDK8 (0.43) | CA2MEN1MAPK8KDM4ECYP1A2 | |
| SCHEMBL11086694 | 0.71 | CA2 (0.42) | ALOX5CA2MEN1MAPK8GAA | |
| SCHEMBL11079970 | 0.71 | KMT2A (0.50) | CA2MEN1MAPK8GAAMAPT | |
| SCHEMBL11211764 | 0.70 | LMNA (0.35) | CA2MEN1MAPK8CYP3A4MAPT | |
| SCHEMBL23330448 | 0.69 | SLC6A4 (0.39) | CA2MEN1MAPK8GAAMAPT | |
| SCHEMBL23330960 | 0.69 | ALOX5 (0.39) | ALOX5CA2MEN1MAPK8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206417-B | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-115124520-A | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2022-09-30 | — | — | CN | disclosed |