Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786830 | 0.90 | MAPT (0.62) | MAPTDHFRCSNK2A1KDM4EKMT2A | |
| SCHEMBL4788288 | 0.87 | DHFR (0.52) | MAPTDHFRCSNK2A1KDM4EKMT2A | |
| SCHEMBL14020392 | 0.87 | CSNK2A1 (0.44) | MAPTCSNK2A1KDM4EKMT2ALMNA | |
| SCHEMBL4787158 | 0.85 | CSNK2A1 (0.43) | MAPTCSNK2A1KDM4EKMT2ALMNA | |
| SCHEMBL4789080 | 0.80 | TDP2 (0.44) | MAPTCSNK2A1KDM4EKMT2ALMNA | |
| SCHEMBL1688966 | 0.80 | MAPT (0.52) | MAPTDHFRKDM4EKMT2ALMNA | |
| SCHEMBL4788538 | 0.79 | MAPT (0.60) | MAPTDHFRKDM4EKMT2ALMNA | |
| SCHEMBL14021034 | 0.78 | DHFR (0.51) | MAPTDHFRCSNK2A1KDM4EKMT2A | |
| SCHEMBL1689005 | 0.77 | MAPT (0.57) | MAPTDHFRKDM4EKMT2ALMNA | |
| SCHEMBL1689130 | 0.77 | MAPT (0.49) | MAPTDHFRKDM4EKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134300-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-11-06 | — | — | WO | claimed |
| WO-2008134300-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008134300-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-11-06 | — | — | WO | disclosed |