Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.43 |
| ▸ | MAT2A | P31153 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
| ▸ | CASP7 | P55210 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788964 | 0.85 | MAPT (0.50) | CSNK2A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL4788288 | 0.83 | DHFR (0.52) | CSNK2A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL14020392 | 0.83 | CSNK2A1 (0.44) | CSNK2A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL1689121 | 0.79 | XDH (0.41) | MAPTKMT2ALMNAALDH1A1TP53 | |
| SCHEMBL4789080 | 0.77 | TDP2 (0.44) | CSNK2A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL4788865 | 0.77 | MAPT (0.43) | MAPTKMT2ALMNAALDH1A1TP53 | |
| SCHEMBL4786830 | 0.75 | MAPT (0.62) | CSNK2A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL1689219 | 0.75 | DRD1 (0.41) | MAPTKMT2ALMNAALDH1A1USP2 | |
| SCHEMBL14021034 | 0.74 | DHFR (0.51) | CSNK2A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL1753380 | 0.67 | MAPT (0.80) | MAPTKMT2ALMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134300-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-11-06 | — | — | WO | claimed |
| WO-2008134300-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008134300-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-11-06 | — | — | WO | disclosed |