Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788497 | 0.97 | HTR3A (0.55) | POLBKMT2AMEN1CHRNA7KCNH2 | |
| SCHEMBL4786204 | 0.87 | EPHX2 (0.60) | CHRNA7KCNH2EPHX2MCHR1MCHR2 | |
| SCHEMBL14041580 | 0.86 | POLB (0.63) | POLBKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL4786227 | 0.86 | EPHX2 (0.59) | CHRNA7KCNH2EPHX2MCHR1MCHR2 | |
| SCHEMBL4788021 | 0.86 | EPHX2 (0.64) | CHRNA7KCNH2EPHX2MCHR1ALDH1A1 | |
| SCHEMBL4787450 | 0.85 | EPHX2 (0.63) | POLBKMT2AMEN1CHRNA7KCNH2 | |
| SCHEMBL4786966 | 0.84 | EPHX2 (0.59) | CHRNA7KCNH2EPHX2MCHR1HTR3A | |
| SCHEMBL4788178 | 0.83 | EPHX2 (0.58) | CHRNA7KCNH2EPHX2MCHR1HTR3A | |
| SCHEMBL4787642 | 0.83 | EPHX2 (0.63) | CHRNA7KCNH2EPHX2MCHR1HTR3A | |
| SCHEMBL4786193 | 0.83 | EPHX2 (0.56) | POLBKMT2AMEN1EPHX2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |