Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4481191 | 0.73 | ALDH1A1 (0.46) | ALOX5KDM4EALDH1A1POLBTSHR | |
| SCHEMBL16455700 | 0.69 | CLK4 (0.50) | ALOX5KDM4EALDH1A1POLBDYRK1A | |
| SCHEMBL7657958 | 0.65 | ALOX5 (0.41) | ALOX5KDM4EALDH1A1POLBDYRK1A | |
| SCHEMBL17808238 | 0.65 | ALDH1A1 (0.46) | ALOX5KDM4EALDH1A1POLBDYRK1A | |
| SCHEMBL5282347 | 0.65 | PTPRC (0.55) | ALOX5PTPRCKDM4EALDH1A1POLB | |
| SCHEMBL10165327 | 0.64 | ALDH1A1 (0.53) | ALOX5KDM4EALDH1A1POLBDYRK1A | |
| SCHEMBL28777714 | 0.64 | MAP2K4 (0.48) | ALOX5KDM4EALDH1A1POLBDYRK1A | |
| SCHEMBL1388344 | 0.62 | DHFR (0.55) | KMT2AHSD17B10MAPTUSP2HTT | |
| SCHEMBL15328790 | 0.62 | BRD4 (1.00) | BRD4 | |
| SCHEMBL15759173 | 0.62 | ALDH1A1 (0.57) | ALOX5KDM4EALDH1A1POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | disclosed |