Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8072699 | 0.89 | ALOX5 (0.51) | ALOX5MEN1KMT2ARAB9ATNKS | |
| SCHEMBL7663113 | 0.80 | ALOX5 (0.53) | ALOX5MEN1KMT2ARAB9ATNKS | |
| SCHEMBL7660819 | 0.70 | KDM4E (0.53) | ALOX5MEN1KMT2ACTNNB1ALDH1A1 | |
| Helioxanthin SCHEMBL2960321 | 0.70 | ALOX5 (0.70) | ALOX5MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8082307 | 0.70 | ALOX5 (0.47) | ALOX5MEN1KMT2ARAB9AALDH1A1 | |
| Helioxanthin SCHEMBL29623971 | 0.70 | ALOX5 (0.70) | ALOX5MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7658336 | 0.68 | ALDH1A1 (0.42) | ALOX5MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL7656174 | 0.68 | ALDH1A1 (0.53) | ALOX5MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL7655721 | 0.67 | ALOX5 (0.49) | ALOX5MEN1KMT2ARAB9APARP1 | |
| SCHEMBL8072490 | 0.67 | ALOX5 (0.56) | ALOX5MEN1KMT2ARAB9APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |