Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | TGM1 | P22735 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789741 | 0.84 | DRD2 (0.43) | L3MBTL1GPR119ALDH1A1 | |
| SCHEMBL941442 | 0.75 | GAA (0.68) | KDM4EGAAL3MBTL1CXCR3PKM | |
| SCHEMBL4754464 | 0.73 | KDM4E (0.67) | KDM4EGAAL3MBTL1CXCR3PKM | |
| SCHEMBL6809004 | 0.71 | GAA (0.60) | KDM4EGAAL3MBTL1CXCR3PKM | |
| SCHEMBL2155799 | 0.71 | KDM4E (0.74) | KDM4EGAAL3MBTL1CXCR3PKM | |
| SCHEMBL3600596 | 0.69 | KDM4E (1.00) | KDM4EGAAL3MBTL1CXCR3HSD11B1 | |
| SCHEMBL27605771 | 0.69 | SMN1; SMN2 (0.55) | KDM4EGAAL3MBTL1HSD11B1MAPT | |
| SCHEMBL3079705 | 0.69 | CYP19A1 (0.51) | SMN1; SMN2POLBALDH1A1CA1CA2 | |
| SCHEMBL942135 | 0.68 | CXCR3 (0.60) | KDM4EGAAL3MBTL1CXCR3PKM | |
| SCHEMBL14581818 | 0.68 | GAA (0.55) | KDM4EGAAL3MBTL1CXCR3HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147763-A1 | MMP INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2008-12-04 | — | — | WO | claimed |
| WO-2008147763-A1 | MMP INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2008-12-04 | — | — | WO | disclosed |
| WO-2008147763-A1 | MMP INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2008-12-04 | — | — | WO | disclosed |