Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789118 | 0.84 | KDM4E (0.53) | GPR119ALDH1A1L3MBTL1 | |
| SCHEMBL5020141 | 0.77 | GPR119 (0.41) | DRD2GPR119DRD4CNR2KMT2A | |
| SCHEMBL4750360 | 0.74 | FPR2 (0.48) | KMT2A | |
| SCHEMBL2155271 | 0.73 | GPR119 (0.59) | GPR119ALDH1A1CNR2KMT2AL3MBTL1 | |
| SCHEMBL4754484 | 0.73 | GPR119 (0.54) | DRD2GPR119DRD4ALDH1A1CNR2 | |
| SCHEMBL30567210 | 0.68 | DEGS1 (0.55) | DRD2GPR119DRD4CNR2KMT2A | |
| SCHEMBL22581718 | 0.68 | DEGS1 (0.55) | DRD2GPR119DRD4CNR2KMT2A | |
| SCHEMBL26758698 | 0.68 | KMT2A (0.45) | DRD2GPR119DRD4CNR2KMT2A | |
| SCHEMBL4789296 | 0.67 | GPR119 (0.43) | DRD2GPR119DRD4CNR2KMT2A | |
| SCHEMBL4958636 | 0.67 | GPR119 (0.46) | DRD2GPR119DRD4ALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147763-A1 | MMP INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2008-12-04 | — | — | WO | claimed |
| WO-2008147763-A1 | MMP INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2008-12-04 | — | — | WO | disclosed |