Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789954 | 0.99 | CHRM3 (0.34) | KDM4ETDP1CHRM3TRPM8MEN1 | |
| SCHEMBL4788453 | 0.87 | KDM4E (0.36) | KDM4ETDP1CHRM3TRPM8MEN1 | |
| SCHEMBL4789357 | 0.87 | POLB (0.35) | CHRM3TRPM8POLBHSP90AA1ALDH1A1 | |
| SCHEMBL4788458 | 0.85 | CHRM3 (0.38) | KDM4ETDP1CHRM3TRPM8MEN1 | |
| SCHEMBL4789873 | 0.84 | CHRM3 (0.39) | KDM4ETDP1CHRM3TRPM8ALDH1A1 | |
| SCHEMBL4789676 | 0.83 | POLB (0.32) | TDP1TRPM8MEN1KMT2APOLB | |
| SCHEMBL4788059 | 0.81 | CHRM3 (0.37) | CHRM3TRPM8ALDH1A1LMNATSHR | |
| SCHEMBL4789177 | 0.80 | CCR3 (0.33) | TRPM8POLBHSP90AA1ALDH1A1TSHR | |
| SCHEMBL4790066 | 0.80 | KDM4E (0.35) | KDM4ETDP1CHRM3TRPM8MEN1 | |
| SCHEMBL4789938 | 0.79 | KDM4E (0.35) | KDM4ECHRM3TRPM8ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |