Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790238 | 0.95 | ALDH1A1 (0.35) | HTR2AHTR2CHTR2BNPSR1ALDH1A1 | |
| SCHEMBL4789357 | 0.89 | POLB (0.35) | POLBHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL4788351 | 0.85 | ALDH1A1 (0.34) | HTR2AHTR2CHTR2BNPSR1ALDH1A1 | |
| SCHEMBL4789954 | 0.84 | CHRM3 (0.34) | POLBHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL4788059 | 0.83 | CHRM3 (0.37) | HTR2AHTR2CHTR2BALDH1A1TSHR | |
| SCHEMBL4789922 | 0.83 | KDM4E (0.35) | POLBHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL4789938 | 0.82 | KDM4E (0.35) | HTR2AHTR2CHTR2BALDH1A1TSHR | |
| SCHEMBL4789177 | 0.82 | CCR3 (0.33) | POLBHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL4789383 | 0.80 | CHRM3 (0.36) | HTR2AHTR2CHTR2BALDH1A1TSHR | |
| SCHEMBL4788465 | 0.79 | CHRM3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |