Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 5/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LIPC | P11150 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754311 | 0.83 | PLA2G7 (0.40) | PLA2G7LIPCLIPGHDAC6 | |
| SCHEMBL1743726 | 0.80 | TYR (0.39) | PLA2G7CA2KDM4EHDAC6 | |
| SCHEMBL16118975 | 0.78 | MGLL (0.39) | PLA2G7HDAC6 | |
| SCHEMBL12937829 | 0.77 | TAAR1 (0.41) | KDM4EALDH1A1MAPK1HSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL12802754 | 0.75 | TAAR1 (0.40) | KDM4EALDH1A1MAPK1HSD17B10MEN1 | |
| SCHEMBL16859234 | 0.72 | ALDH1A1 (0.44) | PLA2G7KDM4EALDH1A1LMNA | |
| SCHEMBL7011901 | 0.72 | PTPN1 (0.42) | KDM4EALDH1A1HSD17B10LMNAHTT | |
| SCHEMBL17987095 | 0.72 | HDAC6 (0.37) | PLA2G7KDM4EHDAC6 | |
| SCHEMBL1742996 | 0.72 | TUBB4A (0.36) | PLA2G7CYP4F2CYP4A11KDM4EALDH1A1 | |
| SCHEMBL13981822 | 0.71 | HRH3 (0.37) | PLA2G7ALDH1A1MAPK1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149053-A1 | BICYCL0 [2. 2. 1] HE PT- 2-YLAMINE DERIVATES AND THEIR USE | ARGENTA DISCOVERY LTD. (GB) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008149053-A1 | BICYCL0 [2. 2. 1] HE PT- 2-YLAMINE DERIVATES AND THEIR USE | ARGENTA DISCOVERY LTD. (GB) | 2008-12-11 | — | — | WO | disclosed |