Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698366 | 0.79 | L3MBTL1 (0.40) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL4559646 | 0.74 | GNAI3 (0.34) | KMT2A | |
| SCHEMBL9697372 | 0.73 | LMNA (0.36) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9697223 | 0.71 | LMNA (0.35) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL5816021 | 0.70 | CYP2B6 (0.43) | KMT2AMAPT | |
| SCHEMBL19799122 | 0.70 | L3MBTL1 (0.34) | L3MBTL1MEN1KMT2ATDP1FDPS | |
| SCHEMBL1077277 | 0.68 | SIGMAR1 (0.33) | KMT2A | |
| SCHEMBL23032951 | 0.67 | L3MBTL1 (0.35) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL21677383 | 0.67 | L3MBTL1 (0.35) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL21440013 | 0.67 | L3MBTL1 (0.35) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124575-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | WO | disclosed |