Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 4/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | SCN1A | P35498 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5461012 | 0.82 | NR3C2 (0.42) | ADORA3LMNAKCNH2TSHRKDM4E | |
| SCHEMBL3016258 | 0.79 | ADORA3 (0.75) | CACNA1CCACNA1DADORA3CACNA1FCACNA1S | |
| SCHEMBL11683170 | 0.77 | TSHR (0.65) | CACNA1CCACNA1DADORA3CACNA1FCACNA1S | |
| SCHEMBL10493291 | 0.77 | ADORA3 (0.56) | CACNA1CCACNA1DADORA3CACNA1FCACNA1S | |
| SCHEMBL10109201 | 0.76 | CACNA1C (0.72) | CACNA1CCACNA1DADORA3CACNA1FCACNA1S | |
| SCHEMBL1672505 | 0.74 | ALDH1A1 (0.47) | CACNA1CCACNA1DADORA3CACNA1FCACNA1S | |
| SCHEMBL11368678 | 0.73 | ADORA3 (0.65) | CACNA1CCACNA1DADORA3CACNA1FCACNA1S | |
| SCHEMBL4608919 | 0.72 | CACNA1C (0.64) | CACNA1CCACNA1DADORA3CACNA1FCACNA1S | |
| SCHEMBL28770058 | 0.72 | ALDH1A1 (0.48) | CACNA1CCACNA1DADORA3CACNA1FCACNA1S | |
| SCHEMBL11688996 | 0.72 | CACNA1D (0.48) | CACNA1CCACNA1DADORA3CACNA1FCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008006070-A2 | COMPOUNDS AND COMBINATIONS THEREOF FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF USE THEREOF | ROSKAMP RESEARCH LLC (US) | 2008-01-10 | — | — | WO | disclosed |
| US-20070191409-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ROSKAMP RESEARCH LLC | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191409-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | APP, PSEN1, PSEN2 | CACNA1C 33/4885CACNA1D 54/4885ADORA3 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.