Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788458 | 0.92 | CHRM3 (0.38) | CHRM3KDM4ETDP1ACHETRPM8 | |
| SCHEMBL4789873 | 0.91 | CHRM3 (0.39) | CHRM3KDM4ETDP1ACHETRPM8 | |
| SCHEMBL4790066 | 0.87 | KDM4E (0.35) | CHRM3KDM4ETDP1TRPM8CCR1 | |
| SCHEMBL4789010 | 0.85 | ALDH1A1 (0.35) | CHRM3TDP1ACHETRPM8CCR1 | |
| SCHEMBL4790311 | 0.82 | CCR1 (0.36) | ACHETRPM8CCR1TSHRALDH1A1 | |
| SCHEMBL4787823 | 0.81 | CCR1 (0.35) | CHRM3ACHETRPM8CCR1 | |
| SCHEMBL4788471 | 0.80 | CHRM3 (0.37) | CHRM3TRPM8TSHRALDH1A1 | |
| SCHEMBL4788453 | 0.79 | KDM4E (0.36) | CHRM3KDM4ETDP1TRPM8CCR1 | |
| SCHEMBL4789922 | 0.78 | KDM4E (0.35) | CHRM3KDM4ETDP1ACHETRPM8 | |
| SCHEMBL4788351 | 0.77 | ALDH1A1 (0.34) | CHRM3ACHETRPM8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |