Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788458 | 0.99 | CHRM3 (0.38) | CHRM3KDM4ETDP1TRPM8ACHE | |
| SCHEMBL4789864 | 0.91 | CHRM3 (0.37) | CHRM3KDM4ETDP1TRPM8ACHE | |
| SCHEMBL4788471 | 0.86 | CHRM3 (0.37) | CHRM3TRPM8TSHRALDH1A1HTR2A | |
| SCHEMBL4788453 | 0.86 | KDM4E (0.36) | CHRM3KDM4ETDP1TRPM8TSHR | |
| SCHEMBL4789954 | 0.85 | CHRM3 (0.34) | CHRM3KDM4ETDP1TRPM8ACHE | |
| SCHEMBL4789922 | 0.84 | KDM4E (0.35) | CHRM3KDM4ETDP1TRPM8ACHE | |
| SCHEMBL4788351 | 0.83 | ALDH1A1 (0.34) | CHRM3TRPM8ACHETSHRALDH1A1 | |
| SCHEMBL4789010 | 0.80 | ALDH1A1 (0.35) | CHRM3TDP1TRPM8ACHETSHR | |
| SCHEMBL4788570 | 0.79 | CHRM3 (0.38) | CHRM3ACHETSHRALDH1A1TAAR1 | |
| SCHEMBL4790311 | 0.79 | CCR1 (0.36) | TRPM8ACHETSHRALDH1A1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |