SCHEMBL4789929

SCHEMBL4789929

N=C(Nc1ccccc1)Oc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
GAA P10253 3/20 0.46
MAPT P10636 2/20 0.46
HTT P42858 1/20 0.46
RAD51 Q06609 1/20 0.44
KMT2A Q03164 5/20 0.43
MEN1 O00255 4/20 0.43
CYP3A4 P08684 2/20 0.43
TP53 P04637 2/20 0.43
TSHR P16473 2/20 0.43
TAS2R38 P59533 2/20 0.43
EPHX1 P07099 1/20 0.43
EPHX2 P34913 1/20 0.43
CDK9 P50750 1/20 0.43
CLK4 Q9HAZ1 1/20 0.43
HSD17B10 Q99714 1/20 0.43
RAB9A P51151 3/20 0.42
KDM4E B2RXH2 1/20 0.42
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21396890 0.87 NOX1 (0.47) ALDH1A1SMN1; SMN2GAAMAPTHTT
SCHEMBL13006826 0.87 MAPT (0.50) ALDH1A1SMN1; SMN2GAAMAPTHTT
SCHEMBL3086433 0.79 LTA4H (0.39) ALDH1A1GAAMAPTRAD51KMT2A
SCHEMBL9505592 0.77 TAS2R38 (0.48) ALDH1A1SMN1; SMN2GAAMAPTHTT
SCHEMBL12285498 0.77 RAD51 (0.39) ALDH1A1GAAMAPTRAD51TSHR
SCHEMBL12845610 0.77 MAPT (0.53) ALDH1A1SMN1; SMN2GAAMAPTKMT2A
SCHEMBL13963618 0.76 ATM (0.51) ALDH1A1SMN1; SMN2MAPTHTTKMT2A
SCHEMBL1006629 0.74 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2GAAMAPTHTT
Phenyl Phenylcarbamate SCHEMBL272994 0.74 ALDH1A1 (0.76) ALDH1A1SMN1; SMN2GAAMAPTHTT
SCHEMBL11464040 0.71 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2GAAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023037688-A1 COATING COMPOSITION 関西ペイント株式会社 2023-03-16 WO disclosed
WO-2021150697-A1 N-SUBSTITUTED-3-TRICYCLYL PIPERIDINE DERIVATIVES AS ANTICANCER AND NEUROPROTECTIVE AGENTS ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2021-07-29 WO disclosed
WO-2008123387-A2 WATER-BASED PAINT COMPOSITIONS AND MULTILAYER COATING FILM FORMING METHOD KANSAI PAINT CO., LTD. (JP) 2008-10-16 WO disclosed
EP-1658071-A2 CYANOGUANIDINE-BASED AZOLE COMPOUNDS USEFUL AS MALONYL-COA DECARBOXYLASE INHIBITORS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2006-05-24 EP disclosed
WO-2005037258-A2 CYANOGUANIDINE-BASED AZOLE COMPOUNDS USEFUL AS MALONYL-COA DECARBOXYLASE INHIBITORS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2005-04-28 WO disclosed