SCHEMBL478999

SCHEMBL478999

O=C1C(Cl)=CC(=NCl)C=C1Cl

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31
ALOX12 P18054 2/20 0.31
RECQL P46063 2/20 0.31
KMT2A Q03164 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
USP2 O75604 1/20 0.30
ESR1 P03372 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17413869 0.84 MEN1 (0.33) MEN1ALDH1A1MAPTHPGDALOX12
SCHEMBL11816608 0.72 MEN1 (0.54) MEN1ALDH1A1MAPTHPGDALOX12
SCHEMBL1683186 0.70 TTR (0.44) MEN1ALDH1A1MAPTRECQLKMT2A
SCHEMBL57203 0.69 MEN1 (0.50) MEN1ALDH1A1MAPTHPGDALOX12
SCHEMBL12267615 0.69 MEN1 (0.36) MEN1ALDH1A1MAPTHPGDALOX12
Hydrochloric Acid SCHEMBL28288248 0.67 MEN1 (0.48) MEN1ALDH1A1MAPTHPGDALOX12
SCHEMBL16310730 0.66 ALDH1A1 (0.33) ALDH1A1TDP1
SCHEMBL10073944 0.65 MEN1 (0.33) MEN1ALDH1A1MAPTHPGDALOX12
SCHEMBL5164481 0.65 ALDH1A1 (0.36) MEN1ALDH1A1MAPTKMT2APOLB
SCHEMBL107238 0.65 TXNRD1 (0.37) MEN1MAPTKMT2AESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 375 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111812054-B Online derivatization detection system and method for propofol of optical fiber sensing microfluidic chip 新疆医科大学 2024-11-08 CN claimed
CN-118215665-A Beta-lactamase inhibitor intermediate and preparation method thereof 苏州信诺维医药科技股份有限公司 2024-06-18 CN claimed
CN-118026889-A Method for synthesizing salicylonitrile based on primary Gibbs reagent dehydration 甘肃博克斯生物技术有限公司 2024-05-14 CN claimed
CN-117964616-A Synthesis method and application of JAK inhibitor drug compound 珠海联邦制药股份有限公司 2024-05-03 CN claimed
CN-117924272-A Synthesis method and application of JAK inhibitor drug intermediate 珠海联邦制药股份有限公司 2024-04-26 CN claimed
CN-117645638-A Fullerene derivative, and preparation method and application thereof 中国科学院化学研究所 2024-03-05 CN claimed
US-20230380457-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-30 US claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
US-20230363426-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-16 US claimed
US-11793220-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2023-10-24 US claimed
US-6420181-B1 DETECTING PREFERENTIAL PARTICLE IN SOLUTION; OBTAIN SOLUTION CONTAINING PARTICLE, MIX WITH SOLVENT, INSERT INTO TUBE, INCUBATE WITH CHROMOGENIC DETECTION INDICATOR, MONITOR SAMPLE FOR SIGNAL THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2002-07-16 US claimed
US-20010055786-A1 Screening method for the discovery and directed evolution of oxygenase enzymes CALIFORNIA INSTITUTE OF TECHNOLOGY 2001-12-27 US claimed
WO-2001077368-A1 SCREENING METHOD FOR THE DISCOVERY AND DIRECTED EVOLUTION OF OXYGENASE ENZYMES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2001-10-18 WO claimed
EP-0460996-B1 Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative OREAL (FR) 1994-09-14 EP claimed
US-5180400-A METHOD FOR DYEING KERATINOUS FIBRES USING AN AMINOINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE L'OREAL (FR) 1993-01-19 US claimed
EP-0460996-A1 Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative L'OREAL (FR) 1991-12-11 EP claimed
EP-0376776-A2 Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone L'OREAL (FR) 1990-07-04 EP claimed
EP-0128317-B1 SUBSTITUTED INDONAPHTHOLS USED IN DETECTING IONS MILES INC. (US) 1988-10-05 EP claimed
US-4552697-A NAPHTOL-IMINES, ALKYLBENZENE AND SUCCINIC ANHYDRIDE, MULTISTEP MILES LABORATORIES, INC. (US) 1985-11-12 US claimed
EP-0128317-A2 Substituted indonaphthols used in detecting ions MILES INC. (US) 1984-12-19 EP claimed