SCHEMBL1683186

SCHEMBL1683186

O=C1C(Br)=CC(=NCl)C=C1Br

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.44
ALOX5 P09917 1/20 0.37
PTGS2 P35354 1/20 0.37
MAPT P10636 2/20 0.33
MAPK1 P28482 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
G6PD P11413 1/20 0.33
HTT P42858 1/20 0.33
RECQL P46063 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL478999 0.70 MEN1 (0.31) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL891446 0.67 ALOX5 (0.56) TTRALOX5PTGS2MAPTMAPK1
Hydrochloric Acid SCHEMBL28225131 0.65 ALOX5 (0.54) TTRALOX5PTGS2MAPTMAPK1
SCHEMBL28718131 0.58 ALOX5 (0.46) ALOX5PTGS2MAPTMEN1KMT2A
SCHEMBL2649 0.57 TTR (0.30) TTR
SCHEMBL14129376 0.57 PTPRC (0.48) TTRALOX5PTGS2MAPTMAPK1
SCHEMBL18889482 0.56 PTPRC (0.41) ALOX5PTGS2MAPTMAPK1MEN1
SCHEMBL3275002 0.55 PABPC1 (0.42)
SCHEMBL18992911 0.54 MAPT (0.41) ALOX5PTGS2MAPTMAPK1MEN1
SCHEMBL11504082 0.53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2303588-A2 TEMPORARY TATTOO DECALS FOR DETECTING THE PRESENCE OF AN ANALYTE Kimberly-Clark Worldwide, Inc. (US) 2011-04-06 EP claimed
WO-2010001275-A2 TEMPORARY TATTOO DECALS FOR DETECTING THE PRESENCE OF AN ANALYTE KIMBERLY-CLARK WORLDWIDE, INC. (US) 2010-01-07 WO claimed
US-20090325221-A1 Temporary Tattoo Decals for Detecting the Presence of an Analyte KIMBERLY-CLARK WORLDWIDE, INC. (US) 2009-12-31 US claimed
EP-1194117-B1 AGENT FOR DYEING KERATIN CONTAINING FIBRES HENKEL KGAA (DE) 2005-06-01 EP claimed
US-12545878-B2 Systems and apparatuses for cellular therapeutics manufacture BRUKER CELLULAR ANALYSIS, INC. (US) 2026-02-10 US disclosed
EP-3423433-B1 SULFAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES BIO PHARM SOLUTIONS CO LTD (KR) 2025-12-17 EP disclosed
US-20250179404-A1 SYSTEMS, APPARATUSES, AND METHODS FOR CELLULAR THERAPEUTICS MANUFACTURE BRUKER SPATIAL BIOLOGY, INC. 2025-06-05 US disclosed
CN-118900689-A Oxazolidinone liposome compositions 阿卡格拉医药公司 2024-11-05 CN disclosed
EP-4277974-A1 SYSTEMS, APPARATUSES, AND METHODS FOR CELLULAR THERAPEUTICS MANUFACTURE Berkeley Lights, Inc. (US) 2023-11-22 EP disclosed
CN-117015597-A Systems, devices, and methods for cellular therapeutic agent manufacture 伯克利之光生命科技公司 2023-11-07 CN disclosed
US-20230313107-A1 SYSTEMS AND APPARATUSES FOR CELLULAR THERAPEUTICS MANUFACTURE Berkeley Lights, Inc. (US) 2023-10-05 US disclosed
US-20220325240-A1 SYSTEMS, APPARATUSES, AND METHODS FOR CELLULAR THERAPEUTICS MANUFACTURE BRUKER CELLULAR ANALYSIS, INC. 2022-10-13 US disclosed
WO-2010001275-A2 TEMPORARY TATTOO DECALS FOR DETECTING THE PRESENCE OF AN ANALYTE KIMBERLY-CLARK WORLDWIDE, INC. (US) 2010-01-07 WO disclosed
US-20090325221-A1 Temporary Tattoo Decals for Detecting the Presence of an Analyte KIMBERLY-CLARK WORLDWIDE, INC. (US) 2009-12-31 US disclosed
EP-1029238-B1 SAMPLING AND ANALYSIS OF REACTIONS BY TRAPPING REACTION COMPONENTS ON A SORBENT SYMYX TECHNOLOGIES INC (US) 2004-05-12 EP disclosed
US-6667009-B1 Analysis apparatus comprising blocks having wells and adsorber layers on the surfaces for preferential screening of combinatorial chemistry libraries and transformations SYMYX TECHNOLOGIES, INC. 2003-12-23 US disclosed
EP-1287882-A2 Method for screening a catalyst library Symyx Technologies, Inc. (US) 2003-03-05 EP disclosed
US-6410332-B1 ANALYZING LIBRARY OF MIXTURES; OBTAIN SAMPLE FROM LIBRARY, INCUBATE WITH SORBENT, TRAP PORTION OF SAMPLE ON SORBENT, DETECTING COMPONENTS OF THE FLUID SAMPLE TRAPPED ON THE SORBENT SYMYX TECHNOLOGIES, INC. 2002-06-25 US disclosed
US-4883676-A CONTROLLED COMBUSTION OF SAWDUST THE GRIFFITH LABORATORIES, LIMITED (CA) 1989-11-28 US disclosed
EP-0246847-A2 Liquid smoke THE GRIFFITH LABORATORIES, LIMITED (CA) 1987-11-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545878-B2 Systems and apparatuses for cellular therapeutics manufacture CD4, IL2, ICOS TTR 101/4885ALOX5 3199/4885PTGS2 2880/4885
US-20250179404-A1 SYSTEMS, APPARATUSES, AND METHODS FOR CELLULAR THERAPEUTICS MANUFACTURE ICOS, PBK, NFATC1 TTR 505/4885ALOX5 1680/4885PTGS2 2827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.