Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 6/20 | 0.56 |
| ▸ | GABRD | O14764 | 6/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.56 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.56 |
| ▸ | GABRE | P78334 | 6/20 | 0.56 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.56 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.56 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.56 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrous Acid SCHEMBL29229231 | 0.93 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1913171 | 0.82 | GABRP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2249284 | 0.79 | HSD17B10 (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL339661 | 0.78 | KDM4E (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6297457 | 0.78 | GABRP (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5357531 | 0.78 | GABRP (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21826652 | 0.78 | AKR1C4 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8220004 | 0.78 | KDM4E (0.60) | LCKFYNCA12CA1CA2 | |
| SCHEMBL20640895 | 0.76 | GABRP (0.72) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1998749 | 0.76 | NAPRT (0.42) | LCKFYNCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109821074-B | Intelligent children testicular prosthesis based on implanted silica gel | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | 2021-11-26 | — | — | CN | claimed |
| CN-101863830-B | Synthesis method of 2-amino-5-bromine isonicotinic acid | ZHEJIANG CHIMICA LAB CO LTD | 2012-07-25 | — | — | CN | claimed |
| CN-101863830-A | Synthesis method of 2-amino-5-bromine isonicotinic acid | ZHEJIANG CHIMICA LAB CO LTD | 2010-10-20 | — | — | CN | claimed |
| CN-109821074-B | Intelligent children testicular prosthesis based on implanted silica gel | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | 2021-11-26 | — | — | CN | disclosed |
| CN-109821074-B | Intelligent children testicular prosthesis based on implanted silica gel | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | 2021-11-26 | — | — | CN | disclosed |
| CN-108619095-B | Medical chitosan sterilization spray | 宁波科瑞特动物药业有限公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-109821074-A | A kind of intelligent children testicular prosthese based on implantable silica gel | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | 2019-05-31 | — | — | CN | disclosed |
| CN-109821074-A | A kind of intelligent children testicular prosthese based on implantable silica gel | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | 2019-05-31 | — | — | CN | disclosed |
| CN-108619095-A | A kind of chitosan medical sterilization spray | 宁波科瑞特动物药业有限公司 | 2018-10-09 | — | — | CN | disclosed |
| EP-2632261-B1 | INHIBITORS OF HEPATITIS C VIRUS | PRESIDIO PHARMACEUTICALS INC (US) | 2016-07-13 | — | — | EP | disclosed |
| US-9309260-B2 | Inhibitors of hepatitis C virus | PRESIDIO PHARMACEUTICALS, INC. (US) | 2016-04-12 | — | — | US | disclosed |
| US-20120251497-A1 | INHIBITORS OF HEPATITIS C VIRUS | PRESIDIO PHARMACEUTICALS, INC. | 2012-10-04 | — | — | US | disclosed |
| CN-101863830-B | Synthesis method of 2-amino-5-bromine isonicotinic acid | ZHEJIANG CHIMICA LAB CO LTD | 2012-07-25 | — | — | CN | disclosed |
| CN-101863830-B | Synthesis method of 2-amino-5-bromine isonicotinic acid | ZHEJIANG CHIMICA LAB CO LTD | 2012-07-25 | — | — | CN | disclosed |
| CN-101863830-B | Synthesis method of 2-amino-5-bromine isonicotinic acid | ZHEJIANG CHIMICA LAB CO LTD | 2012-07-25 | — | — | CN | disclosed |
| WO-2012058125-A1 | INHIBITORS OF HEPATITIS C VIRUS | PRESIDIO PHARMACEUTICALS, INC. (US) | 2012-05-03 | — | — | WO | disclosed |
| CN-102321016-A | Synthesis method of 5-bromo-2-methyl 4-hydroxypyridinecarboxylate | SHANDONG INST LIGHT INDUSTRY | 2012-01-18 | — | — | CN | disclosed |
| CN-101863830-A | Synthesis method of 2-amino-5-bromine isonicotinic acid | ZHEJIANG CHIMICA LAB CO LTD | 2010-10-20 | — | — | CN | disclosed |
| CN-101863830-A | Synthesis method of 2-amino-5-bromine isonicotinic acid | ZHEJIANG CHIMICA LAB CO LTD | 2010-10-20 | — | — | CN | disclosed |
| CN-101863830-A | Synthesis method of 2-amino-5-bromine isonicotinic acid | ZHEJIANG CHIMICA LAB CO LTD | 2010-10-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120251497-A1 | INHIBITORS OF HEPATITIS C VIRUS | HAVCR2, LIPC, HCCS | GABRP 2637/4885GABRD 4003/4885GABRA1 3882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.