SCHEMBL5357531

SCHEMBL5357531

Nc1cc(C(=O)O)c(O)cn1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 5/20 0.58
GABRD O14764 5/20 0.58
GABRA1 P14867 5/20 0.58
GABRB1 P18505 5/20 0.58
GABRG2 P18507 5/20 0.58
GABRB3 P28472 5/20 0.58
GABRA5 P31644 5/20 0.58
GABRA3 P34903 5/20 0.58
GABRA2 P47869 5/20 0.58
GABRB2 P47870 5/20 0.58
GABRA4 P48169 5/20 0.58
GABRE P78334 5/20 0.58
GABRA6 Q16445 5/20 0.58
GABRG1 Q8N1C3 5/20 0.58
GABRG3 Q99928 5/20 0.58
GABRQ Q9UN88 5/20 0.58
KDM4E B2RXH2 5/20 0.48
ALDH1A1 P00352 4/20 0.48
KMT2A Q03164 4/20 0.48
MEN1 O00255 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5356192 0.83 GABRP (0.63) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL6297457 0.79 GABRP (0.58) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL23854026 0.78 CA1 (0.45) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL13360236 0.78 CA1 (0.45) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL4790109 0.78 GABRP (0.56) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL20640895 0.78 GABRP (0.72) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL2718554 0.78 GABRP (0.56) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL2716579 0.78 KDM4E (0.63) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL9318569 0.77 KDM4E (0.62) KDM4EALDH1A1KMT2AMEN1TDP1
Hydrochloric Acid SCHEMBL31689940 0.76 KDM4E (0.61) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070015900-A1 Aromatic amide polymer systems and methods for making the same FOWKES STEVEN W 2007-01-18 US disclosed
US-20070015900-A1 Aromatic amide polymer systems and methods for making the same FOWKES STEVEN W 2007-01-18 US disclosed
US-7160978-B2 Aromatic amide polymer systems and methods for making the same FOWKES STEVEN W 2007-01-09 US disclosed
EP-1601710-A4 AROMATIC AMIDE POLYMER SYSTEMS AND METHODS FOR MAKING THE SAME FOWKES STEVEN W (US) 2006-03-29 EP disclosed
EP-1601710-A2 AROMATIC AMIDE POLYMER SYSTEMS AND METHODS FOR MAKING THE SAME Fowkes, Steven W. (US) 2005-12-07 EP disclosed
WO-2005005486-A2 AROMATIC AMIDE POLYMER SYSTEMS AND METHODS FOR MAKING THE SAME FOWKES STEVEN W (US) 2005-01-20 WO disclosed
US-20040171756-A1 Aromatic amide polymer systems and methods for making the same FOWKES STEVEN W (US) 2004-09-02 US disclosed