Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GNRHR | P30968 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4770686 | 0.88 | DCTPP1 (0.51) | MAPTDCTPP1ALDH1A1KDM4ETHRB | |
| SCHEMBL4767575 | 0.88 | L3MBTL1 (0.52) | MAPTTP53ALDH1A1GNRHRL3MBTL1 | |
| SCHEMBL4866686 | 0.82 | MAPT (0.44) | MAPTSMN1; SMN2TP53DCTPP1ALDH1A1 | |
| SCHEMBL4862734 | 0.82 | MAPT (0.44) | MAPTSMN1; SMN2TP53DCTPP1ALDH1A1 | |
| SCHEMBL4866971 | 0.81 | ADORA2B (0.44) | MAPTSMN1; SMN2TP53DCTPP1ALDH1A1 | |
| SCHEMBL5741824 | 0.81 | PDE1A (0.47) | MAPTDCTPP1ALDH1A1KDM4E | |
| SCHEMBL4867853 | 0.80 | MAPT (0.42) | MAPTSMN1; SMN2TP53DCTPP1ALDH1A1 | |
| SCHEMBL4769603 | 0.80 | DCTPP1 (0.46) | MAPTDCTPP1ALDH1A1KDM4ETHRB | |
| SCHEMBL4762307 | 0.79 | DCTPP1 (0.44) | MAPTSMN1; SMN2DCTPP1ALDH1A1L3MBTL1 | |
| SCHEMBL4762278 | 0.79 | DCTPP1 (0.49) | MAPTDCTPP1ALDH1A1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678181-B1 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS INC (US) | 2008-12-31 | — | — | EP | disclosed |