Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | CMA1 | P23946 | 2/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4791799 | 1.00 | NPBWR1 (0.40) | NPBWR1MAPTALDH1A1MAPK1ADORA2A | |
| SCHEMBL4762462 | 0.94 | NPBWR1 (0.44) | NPBWR1MAPTALDH1A1MAPK1ADORA2A | |
| SCHEMBL4762538 | 0.94 | NPBWR1 (0.44) | NPBWR1MAPTALDH1A1MAPK1ADORA2A | |
| SCHEMBL4767375 | 0.93 | ADORA2B (0.38) | ALDH1A1MAPK1ADORA2AADORA2BADORA1 | |
| SCHEMBL4767385 | 0.93 | ADORA2B (0.38) | ALDH1A1MAPK1ADORA2AADORA2BADORA1 | |
| SCHEMBL4794079 | 0.92 | MAPT (0.38) | MAPTALDH1A1MAPK1ADORA2AADORA2B | |
| SCHEMBL4794085 | 0.92 | MAPT (0.38) | MAPTALDH1A1MAPK1ADORA2AADORA2B | |
| SCHEMBL4763642 | 0.90 | ADORA2A (0.35) | ALDH1A1MAPK1ADORA2AADORA2BADORA1 | |
| SCHEMBL4763634 | 0.90 | ADORA2A (0.35) | ALDH1A1MAPK1ADORA2AADORA2BADORA1 | |
| SCHEMBL4769234 | 0.90 | NPBWR1 (0.41) | NPBWR1MAPTALDH1A1MAPK1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678181-B1 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS INC (US) | 2008-12-31 | — | — | EP | disclosed |