SCHEMBL479292

SCHEMBL479292

C[CH]N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.54
ALDH1A1 P00352 2/20 0.54
AOC3 Q16853 1/20 0.50
CARM1 Q86X55 1/20 0.43
PRMT6 Q96LA8 1/20 0.43
PRMT8 Q9NR22 1/20 0.43
CYP2C19 P33261 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42
SLC6A2 P23975 1/20 0.42
HTR2A P28223 1/20 0.42
SLC6A4 P31645 1/20 0.42
ADRA1A P35348 1/20 0.42
OPRK1 P41145 1/20 0.42
SLC6A3 Q01959 1/20 0.42
KCNH2 Q12809 1/20 0.42
USP2 O75604 1/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4528866 0.78 TSHR (0.58) TSHRALDH1A1AOC3CARM1PRMT6
SCHEMBL3371604 0.76 TSHR (0.50) TSHRALDH1A1AOC3CARM1PRMT6
SCHEMBL12159113 0.76 TSHR (0.47) TSHRALDH1A1AOC3CARM1PRMT6
SCHEMBL266738 0.75 ALDH1A1 (0.48) TSHRALDH1A1AOC3CARM1PRMT6
SCHEMBL8335334 0.75 ALDH1A1 (0.48) TSHRALDH1A1AOC3CARM1PRMT6
SCHEMBL26802 0.75 ALDH1A1 (0.48) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL3065135 0.75 TSHR (0.50) TSHRALDH1A1AOC3CARM1PRMT6
SCHEMBL1403755 0.75 ALDH1A1 (0.48) TSHRALDH1A1AOC3NPC1RAB9A
Hydrochloric Acid SCHEMBL3922809 0.73 ALDH1A1 (0.46) TSHRALDH1A1AOC3CARM1PRMT6
SCHEMBL7383502 0.73 G6PC1 (0.50) TSHRALDH1A1AOC3CARM1PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106543839-B Color paint formulation with phosphoric acid functionalized latex binder and associative thickener 罗门哈斯公司 2020-06-19 CN claimed
EP-3144355-B1 PIGMENTED PAINT FORMULATION WITH A PHOSPHORUS ACID FUNCTIONALIZED LATEX BINDER AND AN ASSOCIATIVE THICKENER ROHM & HAAS (US) 2020-04-29 EP claimed
CN-106543848-B Color paint formulation with phosphoric acid functionalized latex binder and associative thickener 罗门哈斯公司 2020-04-17 CN claimed
US-10563072-B2 Deep base paint formulation ROHM AND HAAS COMPANY (US) 2020-02-18 US claimed
EP-3144354-B1 PIGMENTED PAINT FORMULATION WITH A PHOSPHORUS ACID FUNCTIONALIZED LATEX BINDER AND AN ASSOCIATIVE THICKENER ROHM & HAAS (US) 2018-10-31 EP claimed
US-20180112086-A1 DEEP BASE PAINT FORMULATION ROHM AND HAAS COMPANY 2018-04-26 US claimed
EP-3312245-A1 DEEP BASE PAINT FORMULATION Rohm and Haas Company (US) 2018-04-25 EP claimed
US-9745478-B2 Pigmented paint formulation with a phosphorus acid functionalized latex binder and an associative thickener Rohm and Haas Comopany (US) 2017-08-29 US claimed
US-9745492-B2 Pigmented paint formulation with a phosphorus acid functionalized latex binder and an associative thickener ROHM AND HAAS COMPANY (US) 2017-08-29 US claimed
US-20170081529-A1 PIGMENTED PAINT FORMULATION WITH A PHOSPHORUS ACID FUNCTIONALIZED LATEX BINDER AND AN ASSOCIATIVE THICKENER ROHM AND HAAS COMPANY 2017-03-23 US claimed
US-6977264-B2 Substituted piperidines and methods of use AMGEN INC. (US) 2005-12-20 US claimed
US-20050009952-A1 Liquid inks comprising a stable organosol SAMSUNG ELECTRONICS CO. LTD. 2005-01-13 US claimed
US-20040006067-A1 Substituted piperidines and methods of use AMGEN INC. 2004-01-08 US claimed
US-20030220324-A1 Substituted piperazines and methods of use AMGEN INC. 2003-11-27 US claimed
US-20020128349-A1 Liquid inks comprising a stable organosol S-PRINTING SOLUTION CO., LTD. (KR) 2002-09-12 US claimed
EP-1229057-A2 Organosol and liquid inks comprising the same Samsung Electronics Co., Ltd. (KR) 2002-08-07 EP claimed
EP-1205815-A1 Liquid inks comprising surface-treated colorant particles and manufacturing method thereof Samsung Electronics Co., Ltd. (KR) 2002-05-15 EP claimed
US-5786448-A FOR SCREENING, SYNTHESIZING PEPTIDE DERIVATIVES TREGA BIOSCIENCES, INC. (US) 1998-07-28 US claimed
WO-1998019693-A1 COMBINATORIAL LIBRARIES OF CYCLIC UREA AND CYCLIC THIOUREA DERIVATIVES AND COMPOUNDS THEREIN TREGA BIOSCIENCES, INC. (US) 1998-05-14 WO claimed
US-5523399-A MACROLIDE ANTIBIOTICS HAVING A STRONG ANTIBACTERIAL ACTIVITY TAISHO PHARMACEUTICAL CO., LTD. (JP) 1996-06-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030220324-A1 Substituted piperazines and methods of use MC5R, MC4R, MC1R TSHR 271/4885ALDH1A1 686/4885AOC3 1403/4885
US-20040006067-A1 Substituted piperidines and methods of use MC4R, MC5R, MC1R TSHR 303/4885ALDH1A1 423/4885AOC3 1064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.