SCHEMBL8335334

SCHEMBL8335334

S=CN(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
TSHR P16473 2/20 0.48
AOC3 Q16853 1/20 0.44
MGLL Q99685 3/20 0.43
G6PC1 P35575 1/20 0.42
CA2 P00918 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA9 Q16790 1/20 0.41
GAA P10253 1/20 0.40
MAOB P27338 1/20 0.40
CALM1 P0DP23 1/20 0.39
CARM1 Q86X55 1/20 0.39
PRMT6 Q96LA8 1/20 0.39
PRMT8 Q9NR22 1/20 0.39
CYP2C19 P33261 1/20 0.39
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2A P28223 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11821323 0.87 TSHR (0.48) ALDH1A1TSHRAOC3MGLLCA2
SCHEMBL22016404 0.83 TAS2R14 (0.42) ALDH1A1TSHRAOC3MGLLCA2
SCHEMBL11824119 0.78 KCNH2 (0.49) MAOBOPRK1KCNH2
SCHEMBL3249918 0.76 MGLL (0.45) ALDH1A1TSHRAOC3MGLLCA2
SCHEMBL3239638 0.76 TSHR (0.56) ALDH1A1TSHRAOC3MGLLCA2
SCHEMBL3237296 0.76 ALDH1A1 (0.44) ALDH1A1TSHRAOC3MGLLG6PC1
SCHEMBL3251335 0.76 AOC3 (0.52) ALDH1A1TSHRAOC3MGLLG6PC1
SCHEMBL26802 0.75 ALDH1A1 (0.48) ALDH1A1TSHRAOC3G6PC1CA2
SCHEMBL479292 0.75 TSHR (0.54) ALDH1A1TSHRAOC3MGLLG6PC1
SCHEMBL266738 0.75 ALDH1A1 (0.48) ALDH1A1TSHRAOC3MGLLG6PC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170114155-A1 CHEMICALLY FUNCTIONALIZED RENEWED RUBBER COMPOSITION LEHIGH TECHNOLOGIES, INC. (US) 2017-04-27 US disclosed
US-5969150-A FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES THE ROCKEFELLER UNIVERSITY (US) 1999-10-19 US disclosed
EP-0104432-A2 Herbicide and plant growth regulator comprising alpha-beta-unsaturated compound TEIJIN LIMITED (JP) 1984-04-04 EP disclosed