Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CCR9 | P51686 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533479 | 0.86 | DPP4 (0.36) | KMT2ACCR9DPP4LOXL2MMP2 | |
| SCHEMBL7418680 | 0.85 | KMT2A (0.41) | KMT2ACCR9DPP4COMTLOXL2 | |
| SCHEMBL7416794 | 0.81 | LOXL2 (0.42) | KMT2ACCR9DPP4COMTLOXL2 | |
| SCHEMBL7416470 | 0.80 | KMT2A (0.42) | KMT2ACCR9DPP4LOXL2P2RX7 | |
| SCHEMBL17372075 | 0.78 | DPP4 (0.41) | KMT2ADPP4LOXL2CA1CA2 | |
| SCHEMBL4793708 | 0.77 | CCR9 (0.35) | KMT2ACCR9DPP4COMTLOXL2 | |
| SCHEMBL7423716 | 0.75 | DPP4 (0.37) | KMT2ACCR9DPP4LOXL2ALDH1A1 | |
| SCHEMBL7417140 | 0.74 | FEN1 (0.43) | KMT2ADPP4COMTLOXL2ALOX5AP | |
| SCHEMBL18283289 | 0.71 | COMT (0.41) | KMT2ACOMTALDH1A1RAB9ANPSR1 | |
| SCHEMBL7533483 | 0.70 | DPP4 (0.36) | KMT2ADPP4LOXL2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924561-A2 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | Eli Lilly & Company (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007028083-A2 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |