Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
| ▸ | CCR9 | P51686 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4793133 | 0.86 | KMT2A (0.39) | DPP4KMT2ACCR9LOXL2MMP2 | |
| SCHEMBL7423716 | 0.81 | DPP4 (0.37) | DPP4KMT2ANFE2L2CCR9HSP90AA1 | |
| SCHEMBL7418680 | 0.80 | KMT2A (0.41) | DPP4KMT2ANFE2L2CCR9LOXL2 | |
| SCHEMBL17372075 | 0.76 | DPP4 (0.41) | DPP4KMT2ALOXL2MAOBMAOA | |
| SCHEMBL7416794 | 0.76 | LOXL2 (0.42) | DPP4KMT2ACCR9LOXL2 | |
| SCHEMBL7416470 | 0.75 | KMT2A (0.42) | DPP4KMT2ANFE2L2CCR9LOXL2 | |
| SCHEMBL7417140 | 0.73 | FEN1 (0.43) | DPP4KMT2ALOXL2 | |
| Hydrochloric Acid SCHEMBL7365840 | 0.72 | CA2 (0.36) | DPP4KMT2ALOXL2MAOB | |
| SCHEMBL7533483 | 0.72 | DPP4 (0.36) | DPP4KMT2ANFE2L2HSP90AA1HSP90AB1 | |
| SCHEMBL7473666 | 0.71 | TXNRD1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255735-A2 | PYRIDINE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-11-13 | — | — | EP | claimed |
| WO-2001056990-A2 | PYRIDINE DERIVATES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2001-08-09 | — | — | WO | claimed |
| EP-1255735-A2 | PYRIDINE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001056990-A2 | PYRIDINE DERIVATES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |