Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 14/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 13/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064708 | 0.78 | FEN1 (0.49) | FEN1ALOX5APCOMTKMT2A | |
| SCHEMBL17372075 | 0.78 | DPP4 (0.41) | LOXL2DPP4KMT2A | |
| SCHEMBL7416470 | 0.76 | KMT2A (0.42) | LOXL2DPP4KMT2A | |
| SCHEMBL7418680 | 0.75 | KMT2A (0.41) | LOXL2COMTDPP4KMT2A | |
| SCHEMBL15916605 | 0.75 | TDP1 (0.44) | FEN1ALOX5APCOMT | |
| SCHEMBL4793133 | 0.74 | KMT2A (0.39) | FEN1ALOX5APLOXL2COMTDPP4 | |
| SCHEMBL9955204 | 0.73 | PARP1 (0.45) | FEN1ALOX5APCOMTKMT2A | |
| SCHEMBL7533479 | 0.73 | DPP4 (0.36) | LOXL2DPP4KMT2A | |
| SCHEMBL8233996 | 0.73 | CTSB (0.45) | FEN1ALOX5APLOXL2DPP4 | |
| SCHEMBL7423716 | 0.72 | DPP4 (0.37) | FEN1ALOX5APLOXL2DPP4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255735-A2 | PYRIDINE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-11-13 | — | — | EP | claimed |
| WO-2001056990-A2 | PYRIDINE DERIVATES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2001-08-09 | — | — | WO | claimed |