SCHEMBL479459

SCHEMBL479459

COC(N)Cc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.62
SLC6A2 P23975 2/20 0.58
TAAR1 Q96RJ0 2/20 0.58
MAOA P21397 1/20 0.58
SLC6A4 P31645 1/20 0.58
SLC6A3 Q01959 1/20 0.58
SIGMAR1 Q99720 1/20 0.58
CYP2A6 P11509 1/20 0.58
ADORA2A P29274 1/20 0.58
ADORA1 P30542 1/20 0.58
CYP2D6 P10635 1/20 0.54
LAP3 P28838 2/20 0.50
ANPEP P15144 2/20 0.48
ALPI P09923 1/20 0.47
PKM P14618 1/20 0.47
PTGS1 P23219 1/20 0.47
XIAP P98170 1/20 0.47
SLC7A5 Q01650 1/20 0.47
SCN4A P35499 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4950704 1.00 EPHX1 (0.62) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL4950924 1.00 EPHX1 (0.62) EPHX1SLC6A2TAAR1MAOASLC6A4
Iodide SCHEMBL28946993 0.98 EPHX1 (0.60) EPHX1SLC6A2TAAR1MAOASLC6A4
Hydrochloric Acid SCHEMBL28001158 0.98 EPHX1 (0.60) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL6188434 0.88 SRR (0.49) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL11512652 0.84 TAAR1 (0.53) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL16389766 0.80 SLC6A4 (0.44) EPHX1TAAR1SLC6A4CYP2D6
SCHEMBL1049748 0.78 EPHX1 (0.58) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL1204850 0.78 SLC6A2 (0.54) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL7265649 0.78 ANPEP (0.47) EPHX1SLC6A2TAAR1MAOASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 449 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250145472-A1 METHOD FOR GENERATING CARBON DIOXIDE KOBE GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-05-08 US claimed
EP-4480568-A1 METHOD FOR GENERATING CARBON DIOXIDE Kobe Gakuin Educational Foundation (JP) 2024-12-25 EP claimed
WO-2023153506-A1 METHOD FOR GENERATING CARBON DIOXIDE 学校法人神戸学院 2023-08-17 WO claimed
CN-116367565-A Quasi two-dimensional perovskite nanocrystalline modified three-dimensional perovskite solar cell 河北工业大学 2023-06-30 CN claimed
CN-110396115-A The application of the fire retardant of six (4- methoxyphenethylamine base) rings, three phosphonitrile and preparation method UNIV WEIFANG MEDICAL 2019-11-01 CN claimed
CN-106632368-B A kind of preparation method of irinotecan hydrochloride 上海金和生物制药有限公司 2019-03-08 CN claimed
CN-108899155-A A kind of preparation method of rare earth base semiconductor magnetic material 吴江市聚盈电子材料科技有限公司 2018-11-27 CN claimed
EP-2923692-B1 Beta-amino ester compounds and uses thereof LIVING PROOF INC (US) 2018-05-30 EP claimed
CN-106632368-A Preparation method of irinotecan hydrochloride 上海金和生物制药有限公司 2017-05-10 CN claimed
CN-104130257-B One-dimensional organic semiconductor spiral nano-wires with fluorescence response upon organic amine gases, and preparation method and application thereof 中国科学院化学研究所 2017-02-15 CN claimed
US-20030082830-A1 Synthesis of combinatorial libraries of compounds reminiscent of natural products NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-05-01 US claimed
US-6448443-B1 GENERATED FROM DIVERSIFIABLE SCAFFOLDS SYNTHESIZED FROM THE PYRIDINE-BASED TEMPLATE ISONICOTINAMIDE; ALSO PROVIDES A NOVEL ORTHO-NITROBENZYL PHOTOLINKER; SYNTHESIZED FROM A SHIKIMIC ACID BASED EPOXYOL TEMPLATE PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2002-09-10 US claimed
WO-2002043675-A2 IMMOBILISATION OF ACTIVE AGENTS ON FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-06-06 WO claimed
EP-1076649-A1 ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME TREGA BIOSCIENCES, INC. (US) 2001-02-21 EP claimed
US-6127381-A A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY LION BIOSCIENCE AG (DE) 2000-10-03 US claimed
EP-0674232-B1 Recording sheets XEROX CORP (US) 2000-05-31 EP claimed
WO-2000006525-A9 SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS HARVARD COLLEGE (US) 2000-04-20 WO claimed
WO-2000006525-A2 SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2000-02-10 WO claimed
WO-1999055679-A1 ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME TREGA BIOSCIENCES, INC. (US) 1999-11-04 WO claimed
EP-0167451-B1 A NEW PROCESS FOR PREPARING NOVEL N-(ACYLOXY-ALKOXY) CARBONYL DERIVATIVES USEFUL AS BIOREVERSIBLE PRODRUG MOIETIES FOR PRIMARY AND SECONDARY AMINE FUNCTIONS IN DRUGS MERCK & CO. INC. (US) 1990-10-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030082830-A1 Synthesis of combinatorial libraries of compounds reminiscent of natural products TKFC, NISCH, PTGIS EPHX1 19/4885SLC6A2 1819/4885TAAR1 2413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.