Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795076 | 1.00 | ALDH1A1 (0.38) | ALDH1A1KDM4EHTTATMSYK | |
| SCHEMBL4726527 | 0.94 | ALDH1A1 (0.39) | ALDH1A1KDM4ESYKHPGDLMNA | |
| SCHEMBL4726531 | 0.94 | ALDH1A1 (0.39) | ALDH1A1KDM4ESYKHPGDLMNA | |
| SCHEMBL4794530 | 0.94 | KDM4E (0.35) | ALDH1A1KDM4EHTTATMSYK | |
| SCHEMBL4794527 | 0.94 | KDM4E (0.35) | ALDH1A1KDM4EHTTATMSYK | |
| SCHEMBL4155397 | 0.92 | KDM4E (0.38) | ALDH1A1KDM4EHTTATMSYK | |
| SCHEMBL4155399 | 0.92 | KDM4E (0.38) | ALDH1A1KDM4EHTTATMSYK | |
| SCHEMBL4795186 | 0.92 | ALDH1A1 (0.36) | ALDH1A1KDM4EHTTATMSYK | |
| SCHEMBL4795177 | 0.92 | ALDH1A1 (0.36) | ALDH1A1KDM4EHTTATMSYK | |
| SCHEMBL4152953 | 0.90 | KDM4E (0.37) | KDM4EHTTATMSYKPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017688-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-14 | — | — | WO | disclosed |