Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5050665 | 0.80 | TSHR (0.41) | ALDH1A1TSHR | |
| SCHEMBL23501501 | 0.79 | ALOX15 (0.40) | ALOX15LMNAHSD17B10ALDH1A1TSHR | |
| SCHEMBL12565586 | 0.78 | DGAT1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL276842 | 0.78 | — | — | |
| SCHEMBL29105122 | 0.77 | ALOX15 (0.39) | ALOX15LMNAHSD17B10ALDH1A1TSHR | |
| SCHEMBL25961915 | 0.76 | ALOX15 (0.37) | ALOX15LMNAHSD17B10ALDH1A1TSHR | |
| SCHEMBL14448144 | 0.75 | TSHR (0.44) | LMNAHSD17B10ALDH1A1TSHR | |
| SCHEMBL4848438 | 0.74 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL16938896 | 0.72 | — | — | |
| Propionamide SCHEMBL17925395 | 0.72 | MAPT (0.33) | ALOX15LMNAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |