Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794953 | 0.82 | PDE7A (0.38) | DRD2DRD3ALDH1A1KDM4ETSHR | |
| SCHEMBL4793090 | 0.81 | SMN1; SMN2 (0.53) | DRD3ALDH1A1KDM4ETSHRPOLB | |
| SCHEMBL5716237 | 0.80 | DRD2 (0.47) | DRD2DRD3ALDH1A1KDM4ETSHR | |
| SCHEMBL4793365 | 0.79 | NOTUM (0.52) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL13382891 | 0.79 | DRD2 (0.53) | DRD2DRD3ALDH1A1KDM4ETSHR | |
| SCHEMBL5716359 | 0.78 | NPSR1 (0.49) | DRD2DRD3ALDH1A1KDM4ETSHR | |
| SCHEMBL5716477 | 0.77 | ALDH1A1 (0.52) | DRD2DRD3ALDH1A1KDM4ETSHR | |
| SCHEMBL30839785 | 0.75 | HTR1A (0.58) | DRD2DRD3ALDH1A1KDM4ETSHR | |
| SCHEMBL1441614 | 0.75 | HTR1A (0.58) | DRD2DRD3ALDH1A1KDM4ETSHR | |
| SCHEMBL2317409 | 0.75 | HSD17B10 (0.63) | DRD2DRD3ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |