SCHEMBL4795602

SCHEMBL4795602

C=CCOCc1cc(C)c(COCC=C)cc1C

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
HPGD P15428 2/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
KMT2A Q03164 1/20 0.32
GAA P10253 1/20 0.31
SLC5A1 P13866 1/20 0.30
SLC5A2 P31639 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18092263 0.83 ALDH1A1 (0.37) ALDH1A1HPGDLMNAMAPTNPSR1
SCHEMBL21427674 0.80 MEN1 (0.43) ALDH1A1HPGDLMNAMAPTNPSR1
SCHEMBL5597285 0.78 ALDH1A1 (0.45) ALDH1A1MAPTSLC5A1SLC5A2
SCHEMBL18092255 0.75 KMT2A (0.33) ALDH1A1NPSR1MEN1POLBKMT2A
SCHEMBL22504871 0.74 SLC5A1 (0.34) HPGDSLC5A1SLC5A2
SCHEMBL22504885 0.74 MEN1 (0.33) MEN1KMT2A
SCHEMBL11698533 0.73 CYP3A4 (0.41) ALDH1A1HPGDMAPT
SCHEMBL7097064 0.72 ALDH1A1 (0.38) ALDH1A1MEN1KMT2ASLC5A1SLC5A2
SCHEMBL11871516 0.72 AMY1A (0.46) ALDH1A1HPGDLMNAMAPTNPSR1
SCHEMBL18092264 0.72 MAPT (0.37) ALDH1A1HPGDLMNAMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1973989-A2 FLAME RETARDANT RESIN COMPOSITION GENERAL ELECTRIC COMPANY (US) 2008-10-01 EP claimed
WO-2007084664-A2 FLAME RETARDANT RESIN COMPOSITION GENERAL ELECTRIC COMPANY (US) 2007-07-26 WO claimed
US-20070173572-A1 Flame retardant resin composition GENERAL ELECTRIC COMPANY 2007-07-26 US claimed
EP-1973989-A2 FLAME RETARDANT RESIN COMPOSITION GENERAL ELECTRIC COMPANY (US) 2008-10-01 EP disclosed
WO-2007084664-A2 FLAME RETARDANT RESIN COMPOSITION GENERAL ELECTRIC COMPANY (US) 2007-07-26 WO disclosed
US-20070173572-A1 Flame retardant resin composition GENERAL ELECTRIC COMPANY 2007-07-26 US disclosed