SCHEMBL4795696

SCHEMBL4795696

O=[N+]([O-])C(Br)(CO)C(O)O

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2026178 0.86 LMNA (0.52) LMNA
SCHEMBL92233 0.82 LMNA (0.48) LMNA
SCHEMBL15632756 0.82 LMNA (0.48) LMNA
SCHEMBL17707711 0.79 LMNA (0.45) LMNA
SCHEMBL13875108 0.79 LMNA (0.45) LMNA
SCHEMBL5076396 0.77 LMNA (0.43) LMNA
SCHEMBL92189 0.74 LMNA (0.45) LMNA
SCHEMBL9636037 0.73 GSR (0.44) LMNA
SCHEMBL10453157 0.73 LMNA (0.39) LMNA
SCHEMBL10983140 0.72 LMNA (0.38) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080131420-A1 METHODS AND COMPOSITIONS FOR TREATING MUCOSAL INFLAMMATION ACCENTIA, INC. (US) 2008-06-05 US disclosed
WO-2008008494-A2 METHODS AND COMPOSITIONS FOR TREATING MUCOSAL INFLAMMATION ACCENTIA BIOPHARMACEUTICALS, INC. (US) 2008-01-17 WO disclosed
EP-0744171-B1 DENTAL COMPOSITION FOR HYPERSENSITIVE DENTIN SUN MEDICAL CO LTD (JP) 2003-09-03 EP disclosed
EP-0721773-B1 Dental composition for relieving dentin hypersensitivity SUN MEDICAL CO LTD (JP) 2002-03-27 EP disclosed
US-5879663-A Dental composition for dentin hypersensitivity SUN MEDICAL CO., LTD. (JP) 1999-03-09 US disclosed
EP-0744171-A1 DENTAL COMPOSITION FOR HYPERSENSITIVE DENTIN SUN MEDICAL CO., LTD. (JP) 1996-11-27 EP disclosed
EP-0721773-A2 Dental composition for relieving dentin hypersensitivity SUN MEDICAL CO., LTD. (JP) 1996-07-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080131420-A1 METHODS AND COMPOSITIONS FOR TREATING MUCOSAL INFLAMMATION MMP8, MUC1, MPO LMNA 3464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.