Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479493 | 0.93 | RAB9A (0.41) | LMNAKMT2ACSF1RRETSMN1; SMN2 | |
| SCHEMBL479678 | 0.90 | LMNA (0.45) | LMNAKMT2ACSF1RCHKARET | |
| SCHEMBL2123198 | 0.84 | LMNA (0.46) | LMNAKMT2ACSF1RCHKARET | |
| SCHEMBL479893 | 0.84 | LMNA (0.46) | LMNAKMT2ACSF1RCHKARET | |
| SCHEMBL479844 | 0.84 | PSEN1 (0.39) | LMNAKMT2ACSF1RRETMAPK1 | |
| SCHEMBL479847 | 0.83 | PDPK1 (0.39) | LMNAKMT2ACSF1RPSEN1PSEN2 | |
| SCHEMBL479405 | 0.78 | PIM1 (0.43) | KMT2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL479406 | 0.78 | PIM1 (0.43) | KMT2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL479768 | 0.78 | PSEN1 (0.40) | KMT2ACSF1RPSEN1PSEN2APH1B | |
| SCHEMBL3721673 | 0.77 | AURKA (0.37) | LMNAKMT2ACSF1RRETMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |