Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479634 | 0.90 | LMNA (0.40) | LMNAKMT2ACSF1RALDH1A1HPGD | |
| SCHEMBL479893 | 0.87 | LMNA (0.46) | LMNAKMT2ACSF1RALDH1A1HPGD | |
| SCHEMBL2123198 | 0.87 | LMNA (0.46) | LMNAKMT2ACSF1RALDH1A1HPGD | |
| SCHEMBL479493 | 0.82 | RAB9A (0.41) | LMNAKMT2ACSF1RALDH1A1HPGD | |
| SCHEMBL2120501 | 0.82 | ALDH1A1 (0.49) | LMNAKMT2AALDH1A1HPGDGAA | |
| SCHEMBL2120504 | 0.82 | ALDH1A1 (0.49) | LMNAKMT2AALDH1A1HPGDGAA | |
| SCHEMBL480570 | 0.80 | LMNA (0.47) | LMNAKMT2AALDH1A1HPGDGAA | |
| SCHEMBL480571 | 0.80 | LMNA (0.47) | LMNAKMT2AALDH1A1HPGDGAA | |
| SCHEMBL3148056 | 0.80 | ALDH1A1 (0.48) | LMNAKMT2ACSF1RALDH1A1HPGD | |
| SCHEMBL3148039 | 0.80 | ALDH1A1 (0.48) | LMNAKMT2ACSF1RALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |