Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479634 | 0.93 | LMNA (0.40) | RAB9ALMNAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL3148039 | 0.85 | ALDH1A1 (0.48) | RAB9ALMNAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL3148056 | 0.85 | ALDH1A1 (0.48) | RAB9ALMNAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL479678 | 0.82 | LMNA (0.45) | RAB9ALMNAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL2563895 | 0.82 | RAB9A (0.42) | RAB9ALMNAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL479557 | 0.79 | MAPT (0.41) | RAB9ALMNAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL479637 | 0.79 | RAB9A (0.38) | RAB9ALMNAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL479559 | 0.78 | RXFP1 (0.41) | RAB9AMAPK1SMN1; SMN2MAPTRET | |
| SCHEMBL479649 | 0.78 | RXFP1 (0.36) | MAPTRETCSF1R | |
| SCHEMBL479654 | 0.78 | RXFP1 (0.36) | MAPTRETCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |