Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728690 | 0.78 | MEN1 (0.42) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL1646006 | 0.77 | TDP1 (0.45) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL17828682 | 0.76 | CYP3A4 (0.31) | TDP1CYP3A4 | |
| SCHEMBL25041169 | 0.75 | OPRM1 (0.42) | TDP1ALDH1A1MEN1HTTKMT2A | |
| SCHEMBL14483875 | 0.74 | TDP1 (0.43) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL11571612 | 0.74 | ACHE (0.44) | TDP1ALDH1A1TSHRMEN1HTT | |
| Trimethylammonium SCHEMBL8734959 | 0.73 | TDP1 (0.75) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL4904483 | 0.72 | CYP2A6 (0.42) | TDP1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11390900 | 0.72 | TDP1 (0.41) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL22015893 | 0.71 | TDP1 (0.35) | TDP1CYP3A4ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122006631-A | Device for preparing hydrogen fluoride by molecular recognition complexation method and application thereof | 浙江大学衢州研究院 | 2026-05-12 | — | — | CN | disclosed |
| CN-118290630-A | Homo-polymerization and copolymerization reaction of acrylic esters and polar olefins participated by diamino or monoaminophosphine | 青岛大学 | 2024-07-05 | — | — | CN | disclosed |
| EP-3768688-A1 | C-BULKY P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | Université de Bourgogne (FR) | 2021-01-27 | — | — | EP | disclosed |
| US-20200407381-A1 | C-BULKY P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | Université de Bourgogne (FR) | 2020-12-31 | — | — | US | disclosed |
| CN-111868065-A | C-sterically hindered P-chirally derived organophosphorus compounds | 勃艮第大学 | 2020-10-30 | — | — | CN | disclosed |
| WO-2019180084-A1 | C-BULKY P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | Université de Bourgogne (FR) | 2019-09-26 | — | — | WO | disclosed |
| US-7465838-B2 | Chiral diols, their manufacture and ligands and catalysts derived therefrom | CIBA SPECIALTY CHEMICAL CORP. (US) | 2008-12-16 | — | — | US | disclosed |
| US-7321048-B2 | Organometallic compound purification | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2008-01-22 | — | — | US | disclosed |
| US-20070117994-A1 | Organometallic compound purification | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2007-05-24 | — | — | US | disclosed |
| US-20060030737-A1 | Chiral diols, their manufacture and ligands and catalysts derived therefrom | CIBA SPECIALTY CHEMICALS CORP. | 2006-02-09 | — | — | US | disclosed |
| EP-1546077-A2 | CHIRAL DIOLS, THEIR MANUFACTURE AND LIGANDS AND CATALYSTS DERIVED THEREFROM | Ciba SC Holding AG (CH) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031109-A2 | CHIRAL DIOLS, THEIR MANUFACTURE AND LIGANDS AND CATALYSTS DERIVED THEREFROM | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-04-15 | — | — | WO | disclosed |
| US-4313945-A | 7-Thiazolyl-acetamido-cephem derivatives with terminal aminocarboxylic acid grouping | CIBA-GEIGY CORPORATION (US) | 1982-02-02 | — | — | US | disclosed |
| US-4155946-A | CATALYST CONSISTS OF A NICKEL COMPOUND, A TRIALKYL ALUMINUM COMPOUND; PHOSPHOROUS COMPOUND AND A HALOGENATED PHENOL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-05-22 | — | — | US | disclosed |
| US-4145559-A | Esters of 4-substituted 2-methyleneglutaric acids and method for preparing same | ROHM AND HAAS COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407381-A1 | C-BULKY P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | PLCG1, PLCG2, ACHE | TDP1 371/4885CYP3A4 834/4885ESR1 3791/4885 |
| US-20060030737-A1 | Chiral diols, their manufacture and ligands and catalysts derived therefrom | B2M, CYP4F11, CYP2F1 | TDP1 4145/4885CYP3A4 84/4885ESR1 1801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.