Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PYCR1 | P32322 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11571612 | 0.76 | ACHE (0.44) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL4797776 | 0.72 | TDP1 (0.45) | ALDH1A1TAAR1MEN1KMT2ATDP1 | |
| SCHEMBL11916255 | 0.69 | CYP2A6 (0.50) | CYP2A6ALDH1A1TAAR1HDAC8TDP1 | |
| SCHEMBL3757571 | 0.67 | CYP2A6 (0.57) | CYP2A6ALDH1A1TAAR1TDP1ALOX15 | |
| SCHEMBL4276353 | 0.65 | CYP2A6 (0.53) | CYP2A6ALDH1A1TAAR1TDP1ALOX15 | |
| SCHEMBL18508 | 0.65 | — | — | |
| SCHEMBL7613197 | 0.63 | CYP2A6 (0.42) | CYP2A6ALDH1A1HDAC8TDP1ALOX15 | |
| SCHEMBL20560835 | 0.63 | CYP2A6 (0.42) | CYP2A6ALDH1A1HDAC8MEN1KMT2A | |
| SCHEMBL7862932 | 0.63 | CYP2A6 (0.42) | CYP2A6ALDH1A1TAAR1HDAC8ALOX15 | |
| SCHEMBL12440975 | 0.63 | ALDH1A1 (0.68) | CYP2A6ALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080262269-A1 | Monodonor Phosphonite Ligands | RHODIA UK LIMITED (GB) | 2008-10-23 | — | — | US | disclosed |
| EP-1763399-A1 | MONODONOR PHOSPHONITE LIGANDS | Rhodia UK Limited (GB) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006003431-A1 | MONODONOR PHOSPHONITE LIGANDS | RHODIA UK LIMITED (GB) | 2006-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262269-A1 | Monodonor Phosphonite Ligands | OXER1, OXGR1, CBR1 | CYP2A6 427/4885ALDH1A1 142/4885TAAR1 1223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.