Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.59 |
| ▸ | CTSL | P07711 | 9/20 | 0.47 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3014805 | 0.82 | CTSS (0.63) | CTSSCTSLCTSKALOX5EPHX2 | |
| SCHEMBL3014808 | 0.82 | CTSS (0.63) | CTSSCTSLCTSKALOX5EPHX2 | |
| SCHEMBL3024690 | 0.80 | CTSS (0.62) | CTSSCTSLCTSKALOX5EPHX2 | |
| SCHEMBL5359602 | 0.80 | CTSS (0.62) | CTSSCTSLCTSKALOX5EPHX2 | |
| SCHEMBL3024687 | 0.79 | CTSS (0.39) | CTSSCTSLCTSK | |
| SCHEMBL4799862 | 0.79 | CTSS (0.39) | CTSSCTSLCTSK | |
| SCHEMBL5408237 | 0.79 | CTSS (0.44) | CTSSCTSLCTSKALOX5EPHX2 | |
| SCHEMBL5408243 | 0.76 | CTSS (0.53) | CTSSCTSLCTSKALOX5EPHX2 | |
| SCHEMBL6691416 | 0.76 | CTSS (0.53) | CTSSCTSLCTSKALOX5EPHX2 | |
| SCHEMBL4800580 | 0.76 | CTSS (0.63) | CTSSCTSLCTSKNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242671-A1 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2008-10-02 | — | — | US | disclosed |
| US-7384970-B2 | Inhibitors of cathepsin S | IRM LLC (BM) | 2008-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242671-A1 | INHIBITORS OF CATHEPSIN S | CTSS, CTSB, CTSZ | CTSS 1/4885CTSL 11/4885CTSK 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.