Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32681842 | 0.88 | DPP7 (0.35) | USP30HSD11B1DPP7DPP4 | |
| SCHEMBL20744928 | 0.88 | DPP7 (0.35) | USP30HSD11B1DPP7DPP4 | |
| SCHEMBL4887983 | 0.87 | CHRNB2 (0.36) | USP30HSD11B1DPP4 | |
| SCHEMBL25389420 | 0.86 | DPP7 (0.34) | USP30HSD11B1DPP7DPP4 | |
| SCHEMBL3572947 | 0.83 | USP30 (0.33) | USP30DPP4 | |
| SCHEMBL3580062 | 0.83 | USP30 (0.33) | USP30DPP4 | |
| SCHEMBL9348417 | 0.79 | USP30 (0.53) | USP30 | |
| SCHEMBL9790975 | 0.78 | KMT5A (0.42) | — | |
| SCHEMBL20521054 | 0.77 | — | — | |
| SCHEMBL22719845 | 0.75 | TEAD1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008041090-A1 | MALANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONIST PYRIDINONES | PFIZER LIMITED (GB) | 2008-04-10 | — | — | WO | disclosed |
| US-20080085884-A1 | Melanin Concentrating Hormone Receptor-1 Antagonist Pyridinones | PFIZER INC | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085884-A1 | Melanin Concentrating Hormone Receptor-1 Antagonist Pyridinones | MCHR1, MCHR2, MC1R | USP30 2725/4885HSD11B1 177/4885DPP7 2296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.