Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 4/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18017249 | 0.89 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4USP30 | |
| SCHEMBL4798583 | 0.87 | USP30 (0.38) | USP30DPP4HSD11B1 | |
| SCHEMBL24404469 | 0.81 | CHRNB2 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4DPP4 | |
| SCHEMBL9790975 | 0.78 | KMT5A (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4CHRM2 | |
| SCHEMBL18711401 | 0.78 | USP30 (0.53) | USP30 | |
| SCHEMBL14196281 | 0.78 | USP30 (0.53) | USP30 | |
| SCHEMBL34473742 | 0.77 | CHRNB2 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4USP30 | |
| SCHEMBL34473242 | 0.77 | CHRNB2 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4USP30 | |
| SCHEMBL32681842 | 0.76 | DPP7 (0.35) | USP30DPP4HSD11B1 | |
| SCHEMBL20744928 | 0.76 | DPP7 (0.35) | USP30DPP4HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080085884-A1 | Melanin Concentrating Hormone Receptor-1 Antagonist Pyridinones | PFIZER INC | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085884-A1 | Melanin Concentrating Hormone Receptor-1 Antagonist Pyridinones | MCHR1, MCHR2, MC1R | CHRNB2 726/4885CHRNB4 942/4885CHRNA3 761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.