Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20744455 | 0.89 | L3MBTL3 (0.46) | KMT5AL3MBTL3HRH3ALDH1A1CHRM2 | |
| SCHEMBL20744221 | 0.87 | L3MBTL3 (0.45) | KMT5AL3MBTL3HRH3ALDH1A1CHRM2 | |
| SCHEMBL15948708 | 0.85 | CHRNB2 (0.47) | KMT5AL3MBTL3HRH3CHRM2CHRM1 | |
| SCHEMBL12505797 | 0.83 | KMT5A (0.41) | KMT5AL3MBTL3HRH3CHRM2CHRM1 | |
| SCHEMBL9345094 | 0.80 | CHRNB2 (0.51) | KMT5AL3MBTL3CHRM1CHRNB2CHRNB4 | |
| SCHEMBL18909241 | 0.80 | CHRNB2 (0.51) | KMT5AL3MBTL3ALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL4798583 | 0.78 | USP30 (0.38) | — | |
| SCHEMBL4887983 | 0.78 | CHRNB2 (0.36) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL9343895 | 0.78 | GAA (0.45) | ALDH1A1CHRM1 | |
| SCHEMBL16565553 | 0.77 | KMT5A (0.62) | KMT5AL3MBTL3ALDH1A1KMT2ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071999-A | Preparation of 2,7-diazabicyclo[3.3.0]octanes | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |