Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873939 | 0.87 | CHRM3 (0.37) | CHRM2CHRM3CHRM1DAOHPGDS | |
| SCHEMBL13452265 | 0.86 | ESR1 (0.36) | KIF11SMN1; SMN2CHRM2CHRM3NR1H2 | |
| SCHEMBL15534952 | 0.82 | KIF11 (0.41) | RGS12KIF11SMN1; SMN2CHRM2CHRM3 | |
| SCHEMBL3165430 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2CHRM2CHRM3ALDH1A1LMNA | |
| SCHEMBL362964 | 0.78 | TSHR (0.43) | ALDH1A1MEN1KMT2AESR1ALOX15 | |
| SCHEMBL24620635 | 0.78 | MAPT (0.39) | SMN1; SMN2CHRM2CHRM3ALDH1A1LMNA | |
| SCHEMBL5551006 | 0.76 | MAPT (0.49) | SMN1; SMN2ALDH1A1LMNAMEN1MAPT | |
| SCHEMBL2390466 | 0.75 | RGS12 (0.43) | RGS12KIF11SMN1; SMN2CHRM2CHRM3 | |
| SCHEMBL2390819 | 0.75 | RGS12 (0.43) | RGS12KIF11SMN1; SMN2CHRM2CHRM3 | |
| SCHEMBL6547572 | 0.73 | ALDH1A1 (0.43) | SMN1; SMN2CHRM2CHRM3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655293-B1 | Chromene compound and articles comprising the same | TOKUYAMA CORP (JP) | 2010-03-31 | — | — | EP | disclosed |
| US-7332260-B2 | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO)polymer matrices containing them | CORNING INCORPORATED (US) | 2008-02-19 | — | — | US | disclosed |
| EP-1119560-B1 | NAPHTHOPYRANS ANNELATED IN C5-C6, THEIR PREPARATION AND COMPOSITIONS AND (CO) POLYMER MATRICES CONTAINING THEM | CORNING SA (FR) | 2003-03-05 | — | — | EP | disclosed |
| US-6506538-B1 | Ophthalmic lenses, contact lenses, solar protection glasses, filters, camera optics or photographic apparatus optics or other optical devices | CORNING S.A. (FR) | 2003-01-14 | — | — | US | disclosed |
| US-20020197562-A1 | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO)polymer matrices containing them | BREYNE OLIVIER (FR) | 2002-12-26 | — | — | US | disclosed |
| EP-1119560-A1 | NAPHTHOPYRANS ANNELATED IN C5-C6, THEIR PREPARATION AND COMPOSITIONS AND (CO) POLYMER MATRICES CONTAINING THEM | Corning S.A. (FR) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000015628-A1 | NAPHTHOPYRANS ANNELATED IN C5-C6, THEIR PREPARATION AND COMPOSITIONS AND (CO) POLYMER MATRICES CONTAINING THEM | CORNING S.A. (FR) | 2000-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020197562-A1 | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO)polymer matrices containing them | C5, CCNC, C9 | RGS12 4848/4885KIF11 601/4885SMN1; SMN2 3009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.