Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SDHB | P21912 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 10/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20146971 | 0.81 | KDM4E (0.42) | KDM4ENPC1MAPTSDHBLTA4H | |
| SCHEMBL7121720 | 0.78 | LMNA (0.39) | KDM4ENPC1MAPTCA2CA9 | |
| SCHEMBL10062482 | 0.77 | DPP4 (0.48) | KDM4ENPC1MAPTSDHBLTA4H | |
| SCHEMBL19513782 | 0.71 | KDM4E (0.42) | KDM4ENPC1MAPTSDHBLTA4H | |
| SCHEMBL4801105 | 0.70 | LTA4H (0.49) | KDM4ENPC1MAPTCA2CA9 | |
| SCHEMBL14590760 | 0.69 | SREBF2 (0.37) | KDM4ENPC1MAPTSDHBLTA4H | |
| SCHEMBL12264399 | 0.69 | ADK (0.40) | KDM4ENPC1MAPTLTA4HALDH1A1 | |
| Benzene SCHEMBL27668000 | 0.66 | LTA4H (0.45) | KDM4ENPC1MAPTCA2CA9 | |
| SCHEMBL10070116 | 0.66 | DPP4 (0.44) | KDM4ENPC1MAPTLTA4HALDH1A1 | |
| SCHEMBL9976553 | 0.66 | LTA4H (0.53) | KDM4ENPC1MAPTLTA4HALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1900357-A2 | Drug delivery system for hydrophobic drugs | QLT, Inc. (CA) | 2008-03-19 | — | — | EP | disclosed |
| EP-1229937-A2 | USE OF PDT TO INHIBIT INTIMAL HYPERPLASIA | QLT Inc. (CA) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001035996-A2 | USE OF PDT TO INHIBIT INTIMAL HYPERPLASIA | QLT INC. (CA) | 2001-05-25 | — | — | WO | disclosed |
| WO-2001035997-A2 | USE OF LOW-DOSE PDT TO INHIBIT RESTENOSIS | QLT INC. (CA) | 2001-05-25 | — | — | WO | disclosed |