Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TSPO | P30536 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7190668 | 0.87 | RIPK1 (0.57) | RAB9AKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL3014165 | 0.87 | LTB4R (0.67) | ALOX5LTB4RLTB4R2PPARG | |
| SCHEMBL22649426 | 0.86 | ALOX5 (0.56) | ALOX5PTGS1PTGS2L3MBTL1LTB4R | |
| SCHEMBL4449671 | 0.83 | LTB4R (0.55) | ALOX5PTGS1PTGS2L3MBTL1LTB4R | |
| SCHEMBL5314854 | 0.83 | ALOX5 (0.53) | ALOX5PTGS1PTGS2L3MBTL1LTB4R | |
| SCHEMBL6418344 | 0.82 | ALOX5 (0.74) | ALOX5PTGS1PTGS2L3MBTL1RAB9A | |
| SCHEMBL22513467 | 0.82 | MEN1 (0.51) | L3MBTL1KMT2AMEN1 | |
| SCHEMBL14558978 | 0.81 | HTT (0.46) | RAB9AKMT2ALTB4RLTB4R2MEN1 | |
| SCHEMBL25047613 | 0.81 | LTA4H (0.53) | ALOX5PTGS1PTGS2L3MBTL1LTB4R | |
| SCHEMBL20131479 | 0.80 | SMN1; SMN2 (0.59) | ALOX5L3MBTL1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |